Losing the battle of the bulge? For most people, that means struggling to lose weight, but for athletes and bodybuilders, it means being unable to realize the muscle-building gains they want.
The good news is that it’s never been easier to bulk up and build both mass and strength.
You just need to know which tools to use. In this review, we’ll cover GW0742 SARM and whether it’s the right option for your needs.
NOTE: The below supplements are NOT intended for those under the age of 18. If you are under the age of 18, do NOT consider taking them under any circumstances whatsoever.
Also, if you’re planning on joining the military, cease using this (and really any) supplement at least a couple months before going to MEPS.
They can cause a false positive on a drug test, and will affect your chances of joining!
Table of Contents
What Is GW0742 SARM?
Note: Click Here to buy GW-0742 legally online from our #1 rated source, Pure Rawz.
The quest for bigger, bulkier, better-defined muscles is never-ending. The same is true for tools to help burn fat after bulking, during the cutting stage.
In the past, athletes and bodybuilders were forced to do things manually, or resort to drugs like anabolic steroids, along with their host of dangerous side effects.
Fast forward a few years and the world has access to a whole new class of drugs. We’re talking about SARMs – selective androgen receptor modulators.
These drugs (they’re lab-created pharmaceuticals, not natural supplements) can help to build lean muscle mass, burn fat, and even increase bone density.
GW0742 is actually not a SARM. Instead, it’s a PPAR, or proliferator-activated receptor agonist.
However, it’s generally lumped in with SARMs because it has similar effects on the body. It’s very similar to another PPAR labeled as a SARM – Cardarine.
Both drugs share a similar chemical structure, and while Cardarine is older, they both work in a similar way.
In fact, the two drugs only differ by a single atom between compounds.
Both are also manufactured by GlaxoSmithKline (note that GSK has stopped manufacturing Cardarine at the time of this review and the future of GW0742 is unclear as well).1
How Does GW0742 SARM Differ from Other SARMs?
As mentioned, GW0742 is not really a SARM. So, that’s one way it differs right off the bat.
However, it differs in how it affects the body, as well.
GW0742 works similarly to SARMs in a couple of ways. First, it helps build lean muscle.
Second, it helps improve bone density. However, the real benefit of this drug is in how it affects fat in the body.
In that way, it works the same as any other PPAR on the market – it turns fat into a powerful source of energy for the body while dramatically increasing the oxidative capacity of muscle tissue.
What does that mean?
Simply put, it’s well-suited for endurance athletes who need to keep their body fat low, but also need to ensure that their muscles are able to withstand extreme use.
Another way that GW0742 SARM differs from other drugs on the market is that it affects insulin sensitivity in the body.
It is currently being investigated as a potential treatment for Type 2 diabetes in at least one clinical trial involving laboratory rats.2
In comparison, conventional SARMs only build lean muscle mass, enhance strength, and improve bone density.
However, the problem here is one of evidence.
There have been no human trials of any kind with GW0742, which means there is no accurate evidence of its effectiveness.
What Benefits Does GW0742 SARM Offer?
According to anecdotal evidence, GW0742 offers a wide range of benefits, including the following:
Fat Burning
Perhaps the most visible benefit of this PPAR is the ability to burn fat and use it as an energy source for the body.
This drug is able to boost the body’s metabolism and stimulate a change in fuels from carbs to fat, similar to what occurs during ketosis.
It also pulls adipose from the arms, legs, and abdomen (one of the most difficult areas of the body from which to lose fat).
Muscle Oxidative Capacity
The oxidative capacity of muscle tissue has a direct impact on endurance and the ability to complete work over a prolonged period of time.
Think running a marathon or going for a record-long workout in the gym.
With prolonged work comes the ability to burn even more calories, resulting in the clean, lean, cut look you want.
Prevent Muscle Loss
Anyone who has ever tried to burn fat knows that eventually, the body will cannibalize its muscle tissue in order to preserve fat stores against future need.
With GW0742 SARM, that does not occur.
Muscle tissue is maintained, while fat is burned.
Energy Increase
Another benefit from GW0742 SARM is an increase in available energy.
This is in direct contrast to the results most weight loss plans achieve, which leave you feeling drained and lethargic.
Your glucose metabolism is suppressed while the body is encouraged to begin burning more fat reserves.
Other Potential Benefits
There are unsubstantiated claims that GW0742 SARM can offer additional benefits, including reduced total cholesterol, supporting a healthy lipid profile, and reducing inflammation.3
However, these benefits cannot be corroborated as there has been no human testing on this drug.
The Results of Limited Animal Testing
While there has been no human testing with this drug, it has seen limited animal testing.
This revealed the fact that the drug can enlarge the heart in just a few hours, but it also reduces high blood pressure.
Side Effects of GW0742 SARM
While the benefits of GW0742 SARM seem very substantial, the drug also comes with a pretty significant downside.
It’s also important to realize that, because no human testing has been conducted, the full range of side effects is uncertain.
The only known side effect is that GW0742 can increase the size of your heart by activating calcineurin.4
While some publications claim that this is only the case with high doses and frequent use, the fact is that laboratory mice given very low doses developed enlarged hearts in just 12 hours.5
Note that because this drug has never been tested on humans, it is unclear what other side effects it might cause.
How Does GW0742 SARM Work?
The operation of GW0742 SARM in the body is not clear due to a complete lack of human testing.
However, it is thought that it acts similarly to Cardarine, which has seen more extensive animal testing, but no human testing.
Both drugs are considered investigatory only and are not approved for use in humans.
If GW0742 SARM works similarly to Cardarine, it improves the gene expression that stimulates fat metabolism within the body.
This allows it to accelerate fat loss and means that your cutting efforts will yield much more significant results.
It can allow bodybuilders to achieve the ripped physique they want, with better vascularity and much more defined musculature.
GW0742 SARM Ingredients
To be clear, GW0742 SARM is not a supplement, nor is it legal for it to be sold as such, or to be used as an ingredient in supplement formulations.
This is an untested pharmaceutical supposedly only available for testing in highly controlled conditions and for use on laboratory animals only.
It does not include any ingredients – it is a chemical compound called {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-Yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid.
GW0742 Positive Reviews and Complaints
Since GW0742 is relatively new to the market, there aren’t a ton of reviews showing up yet.
With that said, there are a few that I came across in my research.
Here’s just a couple of them:
Helps me getting back on cardio and with the stack I made its has a specific goal of increasing my endurance as my diet contains carbs in a major part.
-Saikrish
OK so here’s a quick breakdown I’m 48 years old 205 pounds of muscle mostly muscle with a little bit of fat around the mid section this stuff is great for boosting your endurance but not the best for burning fat especially at 48 years old with your metabolism as slow as mine.
-Jaime C.
And here’s a Youtube video review that talks about several things you need to know:
How to Use GW0742 SARM
GW0742 SARM is available as a liquid. Users simply dispense drops onto their tongue, or it can be added to a beverage of your choice.
There are no official dosing amounts or schedules.
Most bodybuilders take 10mg per day and cycle for eight weeks or less. It is unclear if the same will happen in humans.
Once the cycle is done, you should follow that with post-cycle therapy to reset your body once more.
It’s important to visit your doctor to determine if your heart has been affected.
Where to Buy GW0742 SARM
You want to ensure that the products you buy are high-quality and effective.
Too many supplement retailers and manufacturers market their products as including specific ingredients when they actually contain little or none of the specified active ingredients.
With that said, we recommend that you pick up GW0742 from Pure Rawz.
They are one of the most legit SARMS providers on the market, and all of their products are 3rd party tested.
Here’s a link to their page on GW0742: www.PureRawz.co/product/gw0742-tablets/
A bag of 54 20mg tablets will run you anywhere from $50 – $88.
They also offer GW0742 in several other varieties, including liquid and capsules.
Conclusion
Is GW0742 SARM the right option for your bodybuilding needs?
It does seem to promise incredible fat-burning benefits and the ability to create the ripped physique that you want. It also may provide additional benefits, such as better insulin control and perhaps blood pressure reduction.
However, the primary side effect (an enlarged heart) cannot be ignored. For many people, this will be enough to completely dissuade them from ever trying the drug, and rightly so.
However, if the risk is worth it to you, this drug might be what you need to achieve the physical condition that you’re after.
If you decide to move forward, we highly recommend that you choose your retailer with care.
Rats Army has been proven to sell the most effective and safe version of GW 0742 on the market, click here to see their page on it.
It is prohibited for use by athletes at any level in most countries around the world.
This can result in a years-long ban from your sport.
References / Resources
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Pelton P. GW-501516 GlaxoSmithKline/Ligand. Curr Opin Investig Drugs. 2006;7(4):360-370. (source)
- Niu HS, Ku PM, Niu CS, Cheng JT, Lee KS. Development of PPAR-agonist GW0742 as antidiabetic drug: study in animals. Drug Des Devel Ther. 2015;9:5625-5632. Published 2015 Oct 14. doi:10.2147/DDDT.S95045 (source)
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Di Paola R, Esposito E, Mazzon E, Paterniti I, Galuppo M, Cuzzocrea S. GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury. J Leukoc Biol. 2010;88(2):291-301. doi:10.1189/jlb.0110053 (source)
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Cheng KC, Chang WT, Li Y, Cheng YZ, Cheng JT, Chen ZC. GW0742 activates peroxisome proliferator-activated receptor δ to reduce free radicals and alleviate cardiac hypertrophy induced by hyperglycemia in cultured H9c2 cells. J Cell Biochem. 2018;119(11):9532-9542. doi:10.1002/jcb.27270 (source)
- Nicole Wagner, Chantal Jehl-Piétri, Pascal Lopez, Joseph Murdaca, Christian Giordano, Chantal Schwartz, Pierre Gounon, Stéphane N. Hatem, Paul Grimaldi, Kay-Dietrich Wagner, Peroxisome proliferator-activated receptor β stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin, Cardiovascular Research, Volume 83, Issue 1, 1 July 2009, Pages 61–71, (source)
See Also
SR9011 Review: Benefits, Dose, Side Effects, & More
LGD-4033 Review: Ligandrol Benefits, Results, Side Effects, & More
Born and raised in Woodbridge, NJ, he graduated from the New Jersey Institute Of Technology with an MBA in eCommerce.His hobbies include beach volleyball, target shooting, and lifting.
Rob is also a Commercially rated pilot and Certified Flight Instructor (CFI), with over 1,500 hours of flight time.
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